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Article

Caspase-1 regulates cellular trafficking via cleavage of the Rab7 adaptor protein RILP.

Biochemical and biophysical research communications - 18 Sept 2018

Adams Abby, Weinman Steven A, Wozniak Ann L

Abstract excerpt

Intracellular trafficking is a tightly regulated cellular process, mediated in part by Rab GTPases and their corresponding effector proteins. Viruses have evolved mechanisms to hijack these processes to promote their lifecycles. Here we describe a mechanism by which cleavage of the Rab7 adaptor protein, RILP (Rab interacting lysosomal protein) is induced by viral infection. We report that RILP is directly cleaved...

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Source

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Identifiers

PMID: 30100068
DOI: 10.1016/j.bbrc.2018.08.013
PMCID: PMC6133719

Genes

RILP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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