Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An association study of 43 SNPs in 16 candidate genes with atorvastatin response.

The pharmacogenomics journal - 1 Jan 2005

Thompson J F, Man M, Johnson K J, Wood L S, Lira M E, Lloyd D B, Banerjee P, Milos P M, Myrand S P, Paulauskis J, Milad M A, Sasiela W J

Abstract excerpt

Variation in individual response to statin therapy has been widely studied for a potential genetic component. Multiple genes have been identified as potential modulators of statin response, but few study findings have replicated. To further examine these associations, 2735 individuals on statin therapy, half on atorvastatin and the other half divided among fluvastatin, lovastatin, pravastatin and simvastatin were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein E2
Share to Atorvastatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, HDL

Share to Cholesterol, LDL

Share to Heptanoic Acids

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Hydroxymethylglutaryl CoA Reductases

Share to Pyrroles

Source

Identifiers

PMID: 16103896
DOI: 10.1038/sj.tpj.6500328

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An association study of 43 SNPs in 16 candidate genes with atorvastatin response.PMID 16103896Read ↗

Seventeen years of statin pharmacogenetics: a systematic review.Semantic proximity Read ↗

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.Semantic proximity Read ↗

Pharmacogenetic study of statin therapy and cholesterol reduction.Semantic proximity Read ↗

Genetic contribution to lipid target achievement with statin therapy: a prospective study.Semantic proximity Read ↗

Genetic determinants of lipid-lowering response to atorvastatin therapy in an Indian population.Semantic proximity Read ↗

The pharmacogenomics of statins.Semantic proximity Read ↗

The genetic determinants of atorvastatin response.Semantic proximity Read ↗

Genetic variants in genes related to lipid metabolism and atherosclerosis, dyslipidemia and atorvastatin response.Semantic proximity Read ↗

A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering.Semantic proximity Read ↗

CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin.Semantic proximity Read ↗

Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly.Semantic proximity Read ↗

Impact of variants within seven candidate genes on statin treatment efficacy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.