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Article

Topoisomerase II suppresses the temperature sensitivity of Saccharomyces cerevisiae pds5 mutants, but not the defect in sister chromatid cohesion.

Cell cycle (Georgetown, Tex.) - 1 Sept 2005

Aguilar Cristina, Davidson Christian, Dix Melissa, Stead Kristen, Zheng Ke, Hartman Theresa, Guacci Vincent

Abstract excerpt

Sister chromatid cohesion enables chromosomes to achieve bipolar attachment to the mitotic spindle and its dissolution is required for chromosome segregation. The cohesin complex serves as the primary molecular glue responsible for cohesion. Pds5p binds to the same chromosomal loci as the cohesin complex but plays a distinct role as a regulator of cohesion maintenance. Catenation between sister chromatids must...

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PMID: 16096371
DOI: 10.4161/cc.4.9.1997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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