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Article

A somatically mutated V kappa IV gene encoding a human rheumatoid factor light chain.

Clinical and experimental immunology - 1 Jun 1992

Gause A, Küppers R, Mierau R

Abstract excerpt

The light chain of an IgA kappa rheumatoid factor (RF) produced by a hybridoma derived from a patient with rheumatoid arthritis (RA) has been shown to belong to the V kappa IV family. This RF light chain has 31 nucleotide differences compared with the single V kappa IV germline gene reported for the human genome. The patient's V kappa IV germline gene was sequenced, using the polymerase chain reaction (PCR), and...

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Source

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Identifiers

PMID: 1606727
DOI: 10.1111/j.1365-2249.1992.tb06467.x
PMCID: PMC1554512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A somatically mutated V kappa IV gene encoding a human rheumatoid factor light chain.PMID 1606727Read ↗

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