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Article

HANP1/H1T2, a novel histone H1-like protein involved in nuclear formation and sperm fertility.

Molecular and cellular biology - 1 Aug 2005

Tanaka Hiromitsu, Iguchi Naoko, Isotani Ayako, Kitamura Kouichi, Toyama Yoshiro, Matsuoka Yasuhiro, Onishi Masayoshi, Masai Kumiko, Maekawa Mamiko, Toshimori Kiyotaka, Okabe Masaru, Nishimune Yoshitake

Abstract excerpt

We cloned a testis-specific cDNA from mice that encodes a histone H1-like, haploid germ cell-specific nuclear protein designated HANP1/H1T2. The HANP1/H1T2 protein was specifically localized to the nuclei of murine spermatids during differentiation steps 5 to 13 but not to the nuclei of mature sperm. HANP1/H1T2 contains an arginine-serine-rich domain and an ATP/GTP binding site, and it binds to DNA, ATP, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16055721
DOI: 10.1128/MCB.25.16.7107-7119.2005
PMCID: PMC1190238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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