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Article

Normal Spermatogenesis in Mice Lacking the Testis-Specific Linker Histone H1t

1 Mar 2000

Abstract excerpt

H1 histones bind to linker DNA and nucleosome core particles and facilitate the folding of chromatin into a more compact structure. Mammals contain seven nonallelic subtypes of H1, including testis-specific subtype H1t, which varies considerably in primary sequence from the other H1 subtypes. H1t is found only in pachytene spermatocytes and early, haploid spermatids, constituting as much as 55% of the linker...

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Identifiers

PMID: 10688658
DOI: 10.1128/mcb.20.6.2122-2128.2000

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Source receipt: pubmed, retrieved 7 Sept 2026.

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