Article
Changes in intranuclear chromatin architecture induce bipolar nuclear localization of histone variant H1T2 in male haploid spermatids.
Developmental biology - 1 Aug 2006
Catena Raffaella, Ronfani Lorenza, Sassone-Corsi Paolo, Davidson Irwin
Abstract excerpt
Spermiogenesis entails a major biochemical and morphological restructuring of the germ cell packing the DNA into the condensed spermatid nucleus. H1T2 is a histone H1 variant selectively and transiently expressed in male haploid germ cells during spermiogenesis that specifically localizes to a chromatin domain at the apical pole under the acrosome. We explored the mechanisms determining polar localization of H1T2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
