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Article

Progenitor stage-specific activity of a cis-acting double GATA motif for Gata1 gene expression.

Molecular and cellular biology - 1 Mar 2015

Moriguchi Takashi, Suzuki Mikiko, Yu Lei, Takai Jun, Ohneda Kinuko, Yamamoto Masayuki

Abstract excerpt

GATA1 is a master regulator of erythropoiesis, expression of which is regulated by multiple discrete cis-acting elements. In this study, we examine the activity of a promoter-proximal double GATA (dbGATA) motif, using a Gata1 bacterial artificial chromosome (BAC)-transgenic green fluorescent protein (GFP) reporter (G1BAC-GFP) mouse system. Deletion of the dbGATA motif led to significant reductions in GFP...

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Source

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Identifiers

PMID: 25535330
DOI: 10.1128/MCB.01011-14
PMCID: PMC4323484

Genes

GATA1
GATA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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