Article
Polymorphisms in the human XPD (ERCC2) gene, DNA repair capacity and cancer susceptibility: an appraisal.
DNA repair - 28 Sept 2005
Clarkson Stuart G, Wood Richard D
Abstract excerpt
Using the human XPD (ERCC2) gene as an example, we evaluate the suggestion that polymorphisms in DNA repair genes lead to decreased DNA repair capacity and to increased cancer susceptibility. This intuitively appealing idea provides the rationale for a large number of studies that have attracted much attention from scientists, clinicians and the general public. Unfortunately, most of this work presupposes that a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.