Article
Association between the XPD/ERCC2 Lys751Gln polymorphism and risk of cancer: evidence from 224 case-control studies.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Nov 2014
Wu Kai-Ge, He Xiao-Feng, Li Yun-Hui, Xie Wei-Bin, Huang Xi
Abstract excerpt
Genetic variations in the xeroderma pigmentosum group D (XPD) gene may increase cancer susceptibility by affecting the capacity for DNA repair. A lot of studies have reported the association of XPD Lys751Gln polymorphism with risk of cancer, but the results remained controversial. Hence, we performed a systematic review and conducted a meta-analysis to explore association of the XPD Lys751Gln polymorphism with...
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