Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ERCC2/XPD gene polymorphisms and cancer risk.

Mutagenesis - 1 Nov 2002

Benhamou Simone, Sarasin Alain

Abstract excerpt

DNA repair of bulky adducts is essential for a normal life, as demonstrated by the existence of rare but dramatic diseases, such as xeroderma pigmentosum (XP), associating DNA repair deficiency and a high cancer proneness. It is plausible that small variations in the efficacy of repair in the normal population may facilitate cancer development in exposed individuals. In order to check this hypothesis,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Helicases
Share to DNA Repair
Share to Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Proteins

Share to Skin Neoplasms

Share to Smoking

Share to Xeroderma Pigmentosum

Share to Xeroderma Pigmentosum Group D Protein

Source

Identifiers

PMID: 12435843
DOI: 10.1093/mutage/17.6.463

Genes

ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ERCC2/XPD gene polymorphisms and cancer risk.PMID 12435843Read ↗

Polymorphisms of DNA repair genes: ADPRT, XRCC1, and XPD and cancer risk in genetic epidemiology.Semantic proximity Read ↗

Association between the XPD/ERCC2 Lys751Gln polymorphism and risk of cancer: evidence from 224 case-control studies.Semantic proximity Read ↗

Polymorphisms in the human XPD (ERCC2) gene, DNA repair capacity and cancer susceptibility: an appraisal.Semantic proximity Read ↗

Common XPD (ERCC2) polymorphisms have no measurable effect on nucleotide excision repair and basal transcription.Semantic proximity Read ↗

ERCC2 /XPD gene polymorphisms and lung cancer: a HuGE review.Semantic proximity Read ↗

XRCC3 and XPD/ERCC2 single nucleotide polymorphisms and the risk of cancer: a HuGE review.Semantic proximity Read ↗

Single nucleotide polymorphisms of the DNA repair gene XPD/ERCC2 alter mRNA expression.Semantic proximity Read ↗

The polymorphism of DNA repair gene ERCC2/XPD Arg156Arg and susceptibility to breast cancer in a Chinese population.Semantic proximity Read ↗

Nucleotide Excision Repair Capacity and XPC and XPD Gene Polymorphism Modulate Colorectal Cancer Risk.Semantic proximity Read ↗

DNA repair gene XPD polymorphisms and cancer risk: a meta-analysis based on 56 case-control studies.Semantic proximity Read ↗

Polymorphisms of the DNA repair gene XPD: correlations with risk of basal cell carcinoma revisited.Semantic proximity Read ↗

XRCC1 and XPD polymorphisms and esophageal adenocarcinoma risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.