Article
Meta-analysis of two ERCC2 (XPD) polymorphisms, Asp312Asn and Lys751Gln, in breast cancer.
Breast cancer research and treatment - 1 Nov 2010
Pabalan Noel, Francisco-Pabalan Ofelia, Sung Lillian, Jarjanazi Hamdi, Ozcelik Hilmi
Abstract excerpt
The excision repair cross-complementing group 2 gene (ERCC2) plays a key role in DNA repair. Several polymorphisms in the ERCC2 gene have been described, including the commonly occurring Lys751Gln and Asp312Asn polymorphisms. Studies investigating the association of these polymorphisms with breast cancer risk produced controversial results. To evaluate these associations presented in diverse populations, we have...
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