Article
DNA repair gene XPD polymorphisms and cancer risk: a meta-analysis based on 56 case-control studies.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2008
Wang Fan, Chang Dong, Hu Fu-lan, Sui Hong, Han Bing, Li Dan-dan, Zhao Ya-shuang
Abstract excerpt
Genetic variations in the XPD gene may increase cancer susceptibility by affecting the capacity for DNA repair. Several studies have investigated this possibility; however, the conclusions remain controversial. Therefore, we did a systematic review and executed a meta-analysis to explore the association. From 56 studies, a total of 61 comparisons included 25,932 cases and 27,733 controls concerning the Lys 751Gln...
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