Article
The polymorphism of DNA repair gene ERCC2/XPD Arg156Arg and susceptibility to breast cancer in a Chinese population.
Biochemical genetics - 1 Aug 2009
Yin Jiaoyang, Liang Duohong, Vogel Ulla, Chang Yaping, Liu Zhengrong, Yue Li, Sun Xiaoling, Qi Rong, Song Tiehua
Abstract excerpt
Polymorphisms in DNA repair genes are good candidates for modifying cancer risk. ERCC2/XPD, a gene involved in nucleotide excision repair and basal transcription, may influence individual DNA repair capacity, particularly of bulky adducts. This is implicated in cancer susceptibility. To detect the association between ERCC2/XPD Arg156Arg and susceptibility to breast cancer in a Chinese population, we conducted a...
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