Article
The association of six non-synonymous variants in three DNA repair genes with hepatocellular carcinoma risk: a meta-analysis.
Journal of cellular and molecular medicine - 1 Nov 2016
Shi Yan-Hui, Wang Bin, Xu Bai-Ping, Jiang Dan-Na, Zhao Dong-Mei, Ji Man-Ru, Zhou Li, Li Xue, Lu Chang-Zhu
Abstract excerpt
Hepatocellular carcinoma is a complex polygenic disease. Despite the huge advances in genetic epidemiology, it still remains a challenge to unveil the genetic architecture of hepatocellular carcinoma. We, therefore, decided to meta-analytically assess the association of six non-synonymous coding variants from XRCC1, XRCC3 and XPD genes with hepatocellular carcinoma risk by pooling the results of 20 English...
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