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Article

Meta-analysis of the effect of MDR1 C3435T polymorphism on cyclosporine pharmacokinetics.

Basic & clinical pharmacology & toxicology - 1 Nov 2008

Jiang Zhi-Ping, Wang Yi-Ren, Xu Ping, Liu Rong-Rong, Zhao Xie-Lan, Chen Fang-Ping

Abstract excerpt

The published data revealed conflicting results of the polymorphism of MDR1 exon 26 SNP C3435T on the pharmacokinetics of cyclosporine; thus, the aim was to conduct a meta-analysis of significant magnitude to investigate the influence of SNP C3435T on the pharmacokinetics of cyclosporine. A literature search was conducted to locate the relevant papers by using the PubMed electronic source from 1997 and onwards....

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Identifiers

PMID: 18801030
DOI: 10.1111/j.1742-7843.2008.00300.x

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