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Article

Pharmacogenetics of drug transporters and its impact on the pharmacotherapy.

Current topics in medicinal chemistry - 1 Jan 2004

Sakaeda Toshiyuki, Nakamura Tsutomu, Okumura Katsuhiko

Abstract excerpt

Most drug responses are determined by the interplay of several gene products that influence pharmacokinetics and pharmacodynamics, i.e., drug metabolizing enzymes, drug transporters, and drug targets. With the sequencing of the human genome, it has been estimated that approximately 500-1200 genes code for drug transporters. Concerning the effects of genetic polymorphisms on pharmacotherapy, the best characterized...

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Identifiers

PMID: 15379652
DOI: 10.2174/1568026043387692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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