Article
Improvement of heavy metal stress and toxicity assays by coupling a transgenic reporter in a mutant nematode strain.
Aquatic toxicology (Amsterdam, Netherlands) - 30 Sept 2005
Chu Ka-Wah, Chan Shirley K W, Chow King L
Abstract excerpt
Previous studies have demonstrated that wild type Caenorhabditis elegans displays high sensitivity to heavy metals in a lethality test at a level comparable to that of other bioindicator organisms. Taking advantage of the genetics of this model organism, we have tested a number of mutant strains for enhanced sensitivity in heavy metal induced lethality and stress response. These mutants are defective in genes...
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