Article
C. elegans metallothioneins: new insights into the phenotypic effects of cadmium toxicosis.
Journal of molecular biology - 20 Aug 2004
Swain S C, Keusekotten K, Baumeister R, Stürzenbaum S R
Abstract excerpt
Metallothioneins are considered to be the primary player in the detoxification of and protection from cadmium, a teratogen, mutagen and potentially lethal heavy metal. The nematode Caenorhabditis elegans has only two metallothioneins, mtl-i and mtIl-2, thus making it an ideal organism to investigate the phenotypic effects of cadmium toxicosis. The functional importance of metallothioneins in cadmium trafficking...
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