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Isolating genes involved with genotoxic drug response in the nematode Caenorhabditis elegans using genome-wide RNAi screening.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Schøler Lone Vedel, Møller Tine Hørning, Nørgaard Steffen, Vestergaard Lotte, Olsen Anders

Abstract excerpt

The soil nematode Caenorhabditis elegans has become a popular genetic model organism used to study a broad range of complex biological processes, including development, aging, apoptosis, and DNA damage responses. Many genetic tools and tricks have been developed in C. elegans including knock down of gene expression via RNA interference (RNAi). In C. elegans RNAi can effectively be administrated via feeding the...

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PMID: 22941594
DOI: 10.1007/978-1-61779-998-3_3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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