A high-throughput microplate toxicity screening platform based on Caenorhabditis elegans.

doi:10.1016/j.ecoenv.2022.114089

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Article

A high-throughput microplate toxicity screening platform based on Caenorhabditis elegans.

Ecotoxicology and environmental safety - 15 Oct 2022

Wu Jiaying, Gao Yue, Xi Jing, You Xinyue, Zhang Xiaohong, Zhang Xinyu, Cao Yiyi, Liu Peichuan, Chen Xiang, Luan Yang

Abstract excerpt

Caenorhabditis elegans (C. elegans), an established model organism, has been widely used in environmental toxicology research. However, most of the current toxicity testing methods based on worms are time-consuming. In this study we aimed to develop an automated and highly-integrated platform for high-throughput and in situ toxicity testing. Considering the superiority of C. elegans as a neurotoxicological model,...

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PMID: 36126550
DOI: 10.1016/j.ecoenv.2022.114089

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