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Article

Toxicogenomic responses of the model organism Caenorhabditis elegans to gold nanoparticles.

Environmental science & technology - 3 Apr 2012

Tsyusko Olga V, Unrine Jason M, Spurgeon David, Blalock Eric, Starnes Daniel, Tseng Michael, Joice Greg, Bertsch Paul M

Abstract excerpt

We used Au nanoparticles (Au-NPs) as a model for studying particle-specific effects of manufactured nanomaterials (MNMs) by examining the toxicogenomic responses in a model soil organism, Caenorhabditis elegans . Global genome expression for nematodes exposed to 4-nm citrate-coated Au-NPs at the LC(10) level (5.9 mg·L(-1)) revealed significant differential expression of 797 genes. The levels of expression for...

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PMID: 22372763
DOI: 10.1021/es2033108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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