Article
Calcium moderation of cadmium stress explored using a stress-inducible transgenic strain of Caenorhabditis elegans.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology - 1 Jan 1995
Guven K, Duce J A, de Pomerai D I
Abstract excerpt
In a transgenic strain of Caenorhabditis elegans carrying a stress-inducible lacZ reporter gene, short-term sublethal exposure to heavy metals activates transgene expression. The transgene response to Cd2+ is strongly inhibited by Ca2+ ions; furthermore, Ca2+ reduces the net accumulation of Cd2+...
Topics
- Animals
- Animals, Genetically Modified
- Cadmium
- Caenorhabditis elegans
- Calcimycin
- Calcium
- Dose-Response Relationship, Drug
- Gene Expression Regulation
- Genes, Reporter
- Lanthanum
- Linear Models