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Article

Calcium moderation of cadmium stress explored using a stress-inducible transgenic strain of Caenorhabditis elegans.

Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology - 1 Jan 1995

Guven K, Duce J A, de Pomerai D I

Abstract excerpt

In a transgenic strain of Caenorhabditis elegans carrying a stress-inducible lacZ reporter gene, short-term sublethal exposure to heavy metals activates transgene expression. The transgene response to Cd2+ is strongly inhibited by Ca2+ ions; furthermore, Ca2+ reduces the net accumulation of Cd2+ by worms. Both Ca2+ and a variety of calcium uptake inhibitors (nifedipine, La3+, verapamil) depress the dose response...

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PMID: 7538410
DOI: 10.1016/0742-8413(94)00071-h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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