Ecotoxicity of silver nanoparticles on the soil nematode Caenorhabditis elegans using functional ecotoxicogenomics.

doi:10.1021/es803477u

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Article

Ecotoxicity of silver nanoparticles on the soil nematode Caenorhabditis elegans using functional ecotoxicogenomics.

Environmental science & technology - 15 May 2009

Roh Ji-Yeon, Sim Sang Jun, Yi Jongheop, Park Kwangsik, Chung Kyu Hyuck, Ryu Dong-Young, Choi Jinhee

Abstract excerpt

In the present study, the ecotoxicity of silver nanoparticles (AgNPs) was investigated in Caenorhabditis elegans using survival, growth, and reproduction, as the ecotoxicological endpoints, as well as stress response gene expression. Whole genome microarray was used to screen global changes in C. elegans transcription profiles after AgNPs exposure, followed by quantitative analysis of selected genes. The...

Topics

Animals
Caenorhabditis elegans
Ecotoxicology
Gene Expression Regulation
Genes, Helminth
Metal Nanoparticles
Mutation
Oligonucleotide Array Sequence Analysis
Silver
Soil
Stress, Physiological
Toxicogenetics

Source

Open in PubMed

Identifiers

PMID: 19544910
DOI: 10.1021/es803477u

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