Article
The oncogenicity of Jun.
Leukemia - 1 Jan 1992
Vogt P K, Morgan I M, Håvarstein L, Su H, Hartl M, Schuur E
Abstract excerpt
A mutational analysis of the delta region of the Jun protein shows an inverse correlation between transforming and transactivation potential of the mutant proteins if both properties are measured in chicken embryo fibroblasts. The possibility that Jun acquires oncogenicity not by gain but by loss...
Topics
- Animals
- Cell Differentiation
- Cell Transformation, Neoplastic
- Chick Embryo
- Down-Regulation
- Genes, jun
- Muscles
- Mutation
- Oncogene Protein p65(gag-jun)
- Transcription, Genetic