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Article

Transformation suppressor activity of a Jun transcription factor lacking its activation domain.

Nature - 15 Aug 1991

Lloyd A, Yancheva N, Wasylyk B

Abstract excerpt

The oncoprotein c-Jun is thought to be a mediator of ras transformation as both its synthesis and activity as a transcription factor are stimulated by ras expression. But c-Jun co-operates with ras in transformation assays, suggesting that they act along different pathways (reviewed in ref. 4). Here we show by means of a dominant-negative mutated transcription factor that c-Jun potentially in conjunction with...

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Identifiers

PMID: 1907719
DOI: 10.1038/352635a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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