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Article

Desmoglein 2 is expressed abnormally rather than mutated in familial and sporadic gastric cancer.

The Journal of pathology - 1 Oct 2005

Biedermann Karin, Vogelsang Holger, Becker Ingrid, Plaschke Susanne, Siewert Jörg Rüdiger, Höfler Heinz, Keller Gisela

Abstract excerpt

Alterations of the cell adhesion molecule E-cadherin have been demonstrated in sporadic and hereditary gastric carcinomas. A cell adhesion molecule with functional similarity to E-cadherin is desmoglein 2 (Dsg2), a major component of the desmosomes. In this study, we investigated whether alterations of Dsg2 are involved in gastric carcinogenesis and whether germline mutations contribute to a genetic...

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Identifiers

PMID: 16025435
DOI: 10.1002/path.1821

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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