Article
Genetic screening for hereditary diffuse gastric cancer.
Expert review of molecular diagnostics - 1 Mar 2003
Oliveira Carlo, Seruca Raquel, Caldas Carlos
Abstract excerpt
Knowledge regarding the genetic basis of hereditary diffuse gastric cancer has greatly increased in the past 4 years, namely due to the discovery of segregating germline mutations in the gene coding for E-cadherin, within families with this cancer predisposing syndrome. Members of hereditary diffuse gastric cancer families have predominantly high predisposition to develop diffuse carcinomas of the stomach but can...
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