Genetic screening for hereditary diffuse gastric cancer.

doi:10.1586/14737159.3.2.201

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Article

Genetic screening for hereditary diffuse gastric cancer.

Expert review of molecular diagnostics - 1 Mar 2003

Oliveira Carlo, Seruca Raquel, Caldas Carlos

Abstract excerpt

Knowledge regarding the genetic basis of hereditary diffuse gastric cancer has greatly increased in the past 4 years, namely due to the discovery of segregating germline mutations in the gene coding for E-cadherin, within families with this cancer predisposing syndrome. Members of hereditary diff...

Topics

Gastrectomy
Genetic Counseling
Genetic Predisposition to Disease
Genetic Testing
Germ-Line Mutation
Humans
Pedigree
Penetrance
Polymorphism, Genetic
Stomach Neoplasms

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