Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Transcription Factor Snail Induces Tumor Cell Invasion through Modulation of the Epithelial Cell Differentiation Program

15 Jul 2005

Abstract excerpt

Abberant activation of the process of epithelial-mesenchymal transition in cancer cells is a late event in tumor progression. A key inducer of this transition is the transcription factor Snail, which represses E-cadherin. We report that conditional expression of the human transcriptional repressor Snail in colorectal cancer cells induces an epithelial dedifferentiation program that coincides with a drastic change...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Kruppel-like factors research
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16024625
DOI: 10.1158/0008-5472.can-04-3545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Transcription Factor Snail Induces Tumor Cell Invasion through Modulation of the Epithelial Cell Differentiation ProgramPMID 16024625Read ↗

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.Semantic proximity Read ↗

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells.Semantic proximity Read ↗

The Role of Snail in EMT and TumorigenesisSemantic proximity Read ↗

The Snail genes as inducers of cell movement and survival: implications in development and cancerSemantic proximity Read ↗

Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancerSemantic proximity Read ↗

Epigenetic Regulation of EMT: The Snail StorySemantic proximity Read ↗

The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.Semantic proximity Read ↗

The role of Snail1 transcription factor in colorectal cancer progression and metastasisSemantic proximity Read ↗

The Transcriptional Repressor SNAIL Is Overexpressed in Human Colon CancerSemantic proximity Read ↗

SNAIL1 employs β‐Catenin‐LEF1 complexes to control colorectal cancer cell invasion and proliferationSemantic proximity Read ↗

Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic interventionSemantic proximity Read ↗

Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.