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Article

The Snail genes as inducers of cell movement and survival: implications in development and cancer

27 Jun 2005

Abstract excerpt

The functions of the Snail family of zinc-finger transcription factors are essential during embryonic development. One of their best-known functions is to induce epithelial to mesenchymal transitions (EMTs), which convert epithelial cells into migratory mesenchymal cells. In recent years, many orthologues of the Snail family have been identified throughout the animal kingdom, and their study is providing new...

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PMID: 15983400
DOI: 10.1242/dev.01907

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