Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of Snail1 transcription factor in colorectal cancer progression and metastasis

1 Jan 2015

Abstract excerpt

Snail1 is a zinc-finger transcription factor, which plays a role in colorectal cancer development by silencing E-cadherin expression and inducing epithelialmesenchymal transition (EMT). During EMT tumour cells acquire a mesenchymal phenotype that is responsible for their invasive activities. Consequently, Snail1 expression in colorectal cancer is usually associated with progression and metastasis. Some studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Digestive system and related health
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26557772
DOI: 10.5114/wo.2014.42173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of Snail1 transcription factor in colorectal cancer progression and metastasisPMID 26557772Read ↗

Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic interventionSemantic proximity Read ↗

The Role of Snail in EMT and TumorigenesisSemantic proximity Read ↗

SNAIL1 employs β‐Catenin‐LEF1 complexes to control colorectal cancer cell invasion and proliferationSemantic proximity Read ↗

The Snail genes as inducers of cell movement and survival: implications in development and cancerSemantic proximity Read ↗

RUNX1 regulates TGF-β induced migration and EMT in colorectal cancerSemantic proximity Read ↗

Canonical BMP Signaling Executes Epithelial-Mesenchymal Transition Downstream of SNAIL1Semantic proximity Read ↗

Smad1 promotes colorectal cancer cell migration through Ajuba transactivationSemantic proximity Read ↗

Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancerSemantic proximity Read ↗

The Transcription Factor Snail Induces Tumor Cell Invasion through Modulation of the Epithelial Cell Differentiation ProgramSemantic proximity Read ↗

The Snail Family in Normal and Malignant Haematopoiesis.Semantic proximity Read ↗

The Transcriptional Repressor SNAIL Is Overexpressed in Human Colon CancerSemantic proximity Read ↗

Zeb1 and Snail1 engage miR-200f transcriptional and epigenetic regulation during EMT.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.