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Article

CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers.

International journal of cancer - 1 Sept 2017

Vedeld Hege Marie, Merok Marianne, Jeanmougin Marine, Danielsen Stine A, Honne Hilde, Presthus Gro Kummeneje, Svindland Aud, Sjo Ole H, Hektoen Merete, Eknaes Mette, Nesbakken Arild, Lothe Ragnhild A, Lind Guro E

Abstract excerpt

The prognostic value of CpG island methylator phenotype (CIMP) in colorectal cancer remains unsettled. We aimed to assess the prognostic value of this phenotype analyzing a total of 1126 tumor samples obtained from two Norwegian consecutive colorectal cancer series. CIMP status was determined by analyzing the 5-markers CAGNA1G, IGF2, NEUROG1, RUNX3 and SOCS1 by quantitative methylation specific PCR (qMSP). The...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28542846
DOI: 10.1002/ijc.30796
PMCID: PMC5518206

Genes

BRAF
TTR
IGF2
NEUROG1
RUNX3
SOCS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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