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Article

No association of CpG island methylator phenotype and colorectal cancer survival: population-based study.

British journal of cancer - 22 Nov 2016

Jia Min, Jansen Lina, Walter Viola, Tagscherer Katrin, Roth Wilfried, Herpel Esther, Kloor Matthias, Bläker Hendrik, Chang-Claude Jenny, Brenner Hermann, Hoffmeister Michael

Abstract excerpt

BACKGROUND: Previous studies have shown adverse effects of CpG island methylator phenotype (CIMP) on colorectal cancer (CRC) prognosis. However, sample sizes were often limited and only few studies were able to adjust for relevant molecular features associated with CIMP. The aim of this study was to investigate the impact of CIMP on CRC survival in a large population-based study with comprehensive adjustment....

Topics

Aged
Antineoplastic Agents
Colorectal Neoplasms
CpG Islands
DNA Methylation
Female
Humans
Male
Middle Aged
Phenotype
Survival Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Open in PubMed Open full text

Identifiers

PMID: 27811854
DOI: 10.1038/bjc.2016.361
PMCID: PMC5129826

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27811854-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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