Article
Colorectal Cancer with BRAF D594G Mutation Is Not Associated with Microsatellite Instability or Poor Prognosis.
Oncology - 1 Jan 2016
Amaki-Takao Misato, Yamaguchi Tatsuro, Natsume Soichiro, Iijima Takeru, Wakaume Rika, Takahashi Keiichi, Matsumoto Hiroshi, Miyaki Michiko
Abstract excerpt
OBJECTIVE: BRAF D594G mutations in colorectal cancer patients are not clearly understood. We retrospectively investigated the clinicopathological features of colorectal cancers with BRAF D594G mutations. METHODS: We selected 908 colorectal cancer patients who underwent surgical resection from Jan...
Topics
- Adenocarcinoma
- Adult
- Aged
- Aged, 80 and over
- Angiogenesis Inhibitors
- Antineoplastic Agents
- Bevacizumab
- Cetuximab
- Colorectal Neoplasms
- Drug Resistance, Neoplasm
- ErbB Receptors
- Female
- Humans
- Male
- Microsatellite Instability
- Middle Aged
- Mutation
- Neoplasm Staging