Article
Colorectal Cancer with BRAF D594G Mutation Is Not Associated with Microsatellite Instability or Poor Prognosis.
Oncology - 1 Jan 2016
Amaki-Takao Misato, Yamaguchi Tatsuro, Natsume Soichiro, Iijima Takeru, Wakaume Rika, Takahashi Keiichi, Matsumoto Hiroshi, Miyaki Michiko
Abstract excerpt
OBJECTIVE: BRAF D594G mutations in colorectal cancer patients are not clearly understood. We retrospectively investigated the clinicopathological features of colorectal cancers with BRAF D594G mutations. METHODS: We selected 908 colorectal cancer patients who underwent surgical resection from January 2008 to January 2013, and assessed BRAF, KRAS, microsatellite instability, and CpG island methylator phenotype...
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