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Article

Low microsatellite instability is associated with poor prognosis in stage C colon cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Apr 2005

Kohonen-Corish Maija R J, Daniel Joseph J, Chan Charles, Lin Betty P C, Kwun Sun Young, Dent Owen F, Dhillon Varinderpal S, Trent Ronald J A, Chapuis Pierre H, Bokey E Leslie

Abstract excerpt

PURPOSE: The significance of low microsatellite instability (MSI-L) in colorectal cancer is poorly understood. No clear biologic distinction has been found between MSI-L and microsatellite stable (MSS) colorectal cancer, and these two phenotypes are usually combined when analyzed against the well-defined high MSI (MSI-H) phenotype. Evidence is emerging that an O(6)-methylguanine DNA methyltransferase (MGMT) gene...

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Identifiers

PMID: 15800322
DOI: 10.1200/JCO.2005.00.109

Genes

MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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