Article
BRAF mutation may have different prognostic implications in early- and late-stage colorectal cancer.
Medical oncology (Northwood, London, England) - 1 May 2016
Chen Kuo-Hsing, Lin Yu-Lin, Liau Jau-Yu, Tsai Jia-Huei, Tseng Li-Hui, Lin Liang-In, Liang Jin-Tung, Lin Been-Ren, Hung Ji-Shiang, Chang Yih-Leong, Yeh Kun-Huei, Cheng Ann-Lii
Abstract excerpt
The prognostic implication of BRAF mutant colorectal cancer remains paradoxical. Records of BRAF mutant and wild-type colorectal cancer patients at all stages were reviewed. Clinicopathologic features, including microsatellite instability, CpG islands methylator phenotype, and overall survival, o...
Topics
- Aged
- Colorectal Neoplasms
- CpG Islands
- DNA Methylation
- Female
- Humans
- Kaplan-Meier Estimate
- Male
- Microsatellite Instability
- Middle Aged
- Multivariate Analysis