Article
BRAF mutation may have different prognostic implications in early- and late-stage colorectal cancer.
Medical oncology (Northwood, London, England) - 1 May 2016
Chen Kuo-Hsing, Lin Yu-Lin, Liau Jau-Yu, Tsai Jia-Huei, Tseng Li-Hui, Lin Liang-In, Liang Jin-Tung, Lin Been-Ren, Hung Ji-Shiang, Chang Yih-Leong, Yeh Kun-Huei, Cheng Ann-Lii
Abstract excerpt
The prognostic implication of BRAF mutant colorectal cancer remains paradoxical. Records of BRAF mutant and wild-type colorectal cancer patients at all stages were reviewed. Clinicopathologic features, including microsatellite instability, CpG islands methylator phenotype, and overall survival, of these patients were analyzed. Between 2005 and 2013, 428 colorectal cancer patients were enrolled in this study. The...
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