Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional genomics in early autoimmunity.

Annals of the New York Academy of Sciences - 1 Jun 2005

Melanitou Evie

Abstract excerpt

The molecular mechanisms initiating the autoimmune process in type 1 diabetes mellitus (T1DM) remain unknown, and studies aiming to address this question have been compromised by the difficulty of predicting the disease at an early age both in humans and in animal models. An additional hindrance in selecting individuals at an early age has been the complex genetic inheritance of autoimmune diabetes, implicating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Autoimmunity
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin Antibodies

Share to Lymph Nodes

Share to Mice, Inbred NOD

Share to Pancreas

Share to Radioimmunoassay

Source

Identifiers

PMID: 16014521
DOI: 10.1196/annals.1313.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional genomics in early autoimmunity.PMID 16014521Read ↗

Early and quantal (by litter) expression of insulin autoantibodies in the nonobese diabetic mice predict early diabetes onset.Semantic proximity Read ↗

Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse.Semantic proximity Read ↗

An update on the use of NOD mice to study autoimmune (Type 1) diabetes.Semantic proximity Read ↗

THE NOD MOUSE: A Model of Immune DysregulationSemantic proximity Read ↗

Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression.Semantic proximity Read ↗

Molecular phenotyping of immune cells from young NOD mice reveals abnormal metabolic pathways in the early induction phase of autoimmune diabetes.Semantic proximity Read ↗

Dynamic interaction between T cell-mediated β-cell damage and β-cell repair in the run up to autoimmune diabetes of the NOD mouseSemantic proximity Read ↗

Understanding autoimmune diabetes: insights from mouse models.Semantic proximity Read ↗

The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes.Semantic proximity Read ↗

NOD mice and autoimmunity.Semantic proximity Read ↗

Position β57 of I-A g7 controls early anti-insulin responses in NOD mice, linking an MHC susceptibility allele to type 1 diabetes onsetSemantic proximity Read ↗

Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.