Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic interaction between T cell-mediated β-cell damage and β-cell repair in the run up to autoimmune diabetes of the NOD mouse

26 Jan 2005

Abstract excerpt

In type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, the pathogenic destruction of the insulin-producing pancreatic beta-cells is under the control of and influenced by distinct subsets of T lymphocytes. To identify the critical genes expressed by autoimmune T cells, antigen presenting cells, and pancreatic beta-cells during the evolution of T1DM in the nonobese diabetic (NOD) mouse, and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes and associated disorders
Share to Immune Cell Function and Interaction
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15671250
DOI: 10.1152/physiolgenomics.00173.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic interaction between T cell-mediated β-cell damage and β-cell repair in the run up to autoimmune diabetes of the NOD mousePMID 15671250Read ↗

Molecular phenotyping of immune cells from young NOD mice reveals abnormal metabolic pathways in the early induction phase of autoimmune diabetes.Semantic proximity Read ↗

An update on the use of NOD mice to study autoimmune (Type 1) diabetes.Semantic proximity Read ↗

Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.Semantic proximity Read ↗

Gene Expression Analysis of the Pre-Diabetic Pancreas to Identify Pathogenic Mechanisms and Biomarkers of Type 1 DiabetesSemantic proximity Read ↗

THE NOD MOUSE: A Model of Immune DysregulationSemantic proximity Read ↗

Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse.Semantic proximity Read ↗

TRAJ23 Gene Targeting as a Therapeutic Strategy for Type 1 Diabetes: Implications from NOD Mouse Model StudiesSemantic proximity Read ↗

Multitissue Multiomics Integration Reveals Tissue-Specific Pathways, Gene Networks, and Drug Candidates for Type 1 DiabetesSemantic proximity Read ↗

Independent genetic regulation of T-cell and antigen-presenting cell participation in autoimmune islet inflammation.Semantic proximity Read ↗

Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis.Semantic proximity Read ↗

Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes.Semantic proximity Read ↗

From Pancreatic β-Cell Gene Networks to Novel Therapies for Type 1 DiabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.