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Article

SGK1 as a determinant of kidney function and salt intake in response to mineralocorticoid excess.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Aug 2005

Vallon Volker, Huang Dan Yang, Grahammer Florian, Wyatt Amanda W, Osswald Hartmut, Wulff Peer, Kuhl Dietmar, Lang Florian

Abstract excerpt

Mineralocorticoids modify salt balance by both stimulating salt intake and inhibiting salt loss. Renal salt retention is accomplished by upregulation of reabsorption, an effect partially mediated by serum- and glucocorticoid-inducible kinase 1 (SGK1). The present study explored the contribution of SGK1 to the regulation of renal function, salt intake, and blood pressure during mineralocorticoid excess. DOCA/1%...

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Source

Identifiers

PMID: 16014448
DOI: 10.1152/ajpregu.00731.2004

Genes

SGK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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