Article
Common Variants in Serum/Glucocorticoid Regulated Kinase 1 (SGK1) and Blood Pressure Responses to Dietary Sodium or Potassium Interventions: A family-Based Association Study.
Kidney & blood pressure research - 1 Jan 2015
Chu Chao, Wang Yang, Wang Man, Mu Jian-Jun, Liu Fu-Qiang, Wang Lan, Ren Ke-Yu, Wang Dan, Yuan Zu-Yi
Abstract excerpt
BACKGROUND/AIMS: Serum/Glucocorticoid Regulated Kinase 1 (SGK1) plays a significant role in regulating renal Na(+) reabsorption, K(+) secretion, and blood pressure (BP). This study aimed to assess the association of common genetic variants in the SGK1 gene with BP responses to controlled dietary sodium or potassium interventions. METHODS: A total of 334 subjects from 124 families were recruited from the rural...
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