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Article

Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake.

Journal of human hypertension - 1 Mar 2013

Rao A D, Sun B, Saxena A, Hopkins P N, Jeunemaitre X, Brown N J, Adler G K, Williams J S

Abstract excerpt

Serum- and glucocorticoid-inducible kinase 1 (SGK1) has a central role in epithelial sodium channel (ENaC)-dependent Na(+) transport in the distal nephron. We hypothesized that SGK1 gene variants may contribute to the effect of dietary salt intake on blood pressure (BP) in humans with hypertension, and consequentially influence renin-angiotensin-aldosterone (RAA) system activity. Our study population included 421...

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Source

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Identifiers

PMID: 22648267
DOI: 10.1038/jhh.2012.22
PMCID: PMC3463709

Genes

SGK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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