Article
Spontaneous regression of high-grade cervical dysplasia: effects of human papillomavirus type and HLA phenotype.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2005
Trimble Cornelia L, Piantadosi Steven, Gravitt Patti, Ronnett Brigitte, Pizer Ellen, Elko Andrea, Wilgus Barbara, Yutzy William, Daniel Richard, Shah Keerti, Peng Shiwen, Hung Chienfu, Roden Richard, Wu Tzyy Choou, Pardoll Drew
Abstract excerpt
PURPOSE: Persistent infection with oncogenic human papillomaviruses (HPV) plays a central etiologic role in the development of squamous carcinomas of the cervix and their precursor lesions, cervical intraepithelial neoplasias (CIN). We carried out a prospective observational cohort study evaluating known, quantifiable prognostic variables of clinical behavior in women with high-grade cervical lesions....
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