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Article

Clinical Regression of High-Grade Cervical Intraepithelial Neoplasia Is Associated With Absence of FAM19A4/miR124-2 DNA Methylation (CONCERVE Study).

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Sept 2022

Kremer Wieke W, Dick Stèfanie, Heideman Daniëlle A M, Steenbergen Renske D M, Bleeker Maaike C G, Verhoeve Harold R, van Baal W Marchien, van Trommel Nienke, Kenter Gemma G, Meijer Chris J L M, Berkhof Johannes

Abstract excerpt

PURPOSE: Cervical screening can prevent cancer by detection and treatment of cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3). Screening also results in considerable overtreatment because many CIN2/3 lesions show spontaneous regression when left untreated. In this multicenter longitudinal cohort study of women with untreated CIN2/3, the prognostic value of FAM19A4/miR124-2 methylation was evaluated for...

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Identifiers

PMID: 35512257
DOI: 10.1200/JCO.21.02433
PMCID: PMC9462536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clinical Regression of High-Grade Cervical Intraepithelial Neoplasia Is Associated With Absence of FAM19A4/miR124-2 DNA Methylation (CONCERVE Study).PMID 35512257Read ↗

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