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Article

HPV 16 infection and progression of cervical intra-epithelial neoplasia: analysis of HLA polymorphism and HPV 16 E6 sequence variants.

International journal of cancer - 5 Oct 1998

Bontkes H J, van Duin M, de Gruijl T D, Duggan-Keen M F, Walboomers J M, Stukart M J, Verheijen R H, Helmerhorst T J, Meijer C J, Scheper R J, Stevens F R, Dyer P A, Sinnott P, Stern P L

Abstract excerpt

High-risk human papillomavirus (HPV) infection plays an important role in cervical intra-epithelial neoplasia (CIN), but HPV infection alone is not sufficient for progression to cervical cancer. Several lines of evidence suggest that cellular immune surveillance is important in the control of HPV infection and the development of CIN. The presentation to T cells of target viral peptides in the context of HLA...

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Identifiers

PMID: 9754647
DOI: 10.1002/(sici)1097-0215(19981005)78:2<166::aid-ijc8>3.0.co;2-x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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HPV 16 infection and progression of cervical intra-epithelial neoplasia: analysis of HLA polymorphism and HPV 16 E6 sequence variants.PMID 9754647Read ↗

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