HPV 16 infection and progression of cervical intra-epithelial neoplasia: analysis of HLA polymorphism and HPV 16 E6 sequence variants.

doi:10.1002/(sici)1097-0215(19981005)78:2<166::aid-ijc8>3.0.co;2-x

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Article

HPV 16 infection and progression of cervical intra-epithelial neoplasia: analysis of HLA polymorphism and HPV 16 E6 sequence variants.

International journal of cancer - 5 Oct 1998

Bontkes H J, van Duin M, de Gruijl T D, Duggan-Keen M F, Walboomers J M, Stukart M J, Verheijen R H, Helmerhorst T J, Meijer C J, Scheper R J, Stevens F R, Dyer P A, Sinnott P, Stern P L

Abstract excerpt

High-risk human papillomavirus (HPV) infection plays an important role in cervical intra-epithelial neoplasia (CIN), but HPV infection alone is not sufficient for progression to cervical cancer. Several lines of evidence suggest that cellular immune surveillance is important in the control of HPV...

Topics

Adult
Alleles
Disease Progression
Female
Genetic Variation
Genotype
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Humans
Middle Aged
Oncogene Proteins, Viral
Open Reading Frames
Papillomaviridae

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Papillomavirus E7 Proteins

Papillomavirus Infections

Polymorphism, Genetic

Prospective Studies

Repressor Proteins

Source

Open in PubMed

Identifiers

PMID: 9754647
DOI: 10.1002/(sici)1097-0215(19981005)78:2<166::aid-ijc8>3.0.co;2-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9754647-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.