HLA class II DRB1*1302 allele protects against progression to cervical intraepithelial neoplasia grade 3: a multicenter prospective cohort study.

doi:10.1097/IGC.0b013e3182439500

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Article

HLA class II DRB1*1302 allele protects against progression to cervical intraepithelial neoplasia grade 3: a multicenter prospective cohort study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Mar 2012

Matsumoto Koji, Maeda Hiroo, Oki Akinori, Takatsuka Naoyoshi, Yasugi Toshiharu, Furuta Reiko, Hirata Ranko, Mitsuhashi Akira, Fujii Takuma, Hirai Yasuo, Iwasaka Tsuyoshi, Yaegashi Nobuo, Watanabe Yoh, Nagai Yutaka, Kitagawa Tomoyuki, Yoshikawa Hiroyuki

Abstract excerpt

OBJECTIVE: Genetic variations in human leukocyte antigens (HLA) class II regions may influence the risk of cervical cancer by altering the efficiency of the immune responses to human papillomavirus antigens. This prospective study was designed to evaluate the effects of HLA class II alleles on the natural course of cervical precursor lesions. METHODS: We followed a total of 454 Japanese women with cytological...

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PMID: 22391763
DOI: 10.1097/IGC.0b013e3182439500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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