Article
Local immune response in the microenvironment of CIN2-3 with and without spontaneous regression.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2010
Øvestad Irene Tveiterås, Gudlaugsson Einar, Skaland Ivar, Malpica Anais, Kruse Arnold-Jan, Janssen Emiel A M, Baak Jan P A
Abstract excerpt
Fifteen to thirty percent of cases with histologically confirmed CIN2-3 in cervical biopsies regress spontaneously (ie, show CIN1 or less in the follow-up cervical cone). The balance between immune-reactive cells from the host and high-risk human papillomavirus (hrHPV) genotypes may provide a biological explanation for this phenomenon. We retrospectively studied 55 cases of CIN2-3 in a cervical biopsy with...
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