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Article

Allelic loss of HLA class I facilitates evasion from immune surveillance in cervical intraepithelial neoplasia.

HLA - 1 Jun 2024

Kawase Katsushige, Taguchi Ayumi, Ishizaka Aya, Lin Jason, Ueno Toshihide, Yoshimoto Daisuke, Eguchi Satoko, Mori Seiichiro, Sone Kenbun, Mori Mayuyo, Yonekura Syuji, Hanazawa Toyoyuki, Maeda Daichi, Kukimoto Iwao, Mano Hiroyuki, Osuga Yutaka, Kawana Kei, Kawazu Masahito

Abstract excerpt

Loss of heterozygosity (LOH) has been reported to occur in HLA regions in cervical intraepithelial neoplasia (CIN) and cervical cancer. However, the details of how this is related to the progression of CIN have been unclear. In this study, we examined the human papillomavirus (HPV) antigen-presenting capacity of people with CIN and the significance of LOH of HLA class I in the progression of CIN. It was shown...

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Identifiers

PMID: 38837741
DOI: 10.1111/tan.15509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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