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Article

Integrated analysis of copy number alterations and loss of heterozygosity in human pancreatic cancer using a high-resolution, single nucleotide polymorphism array.

Oncology - 1 Jan 2008

Lin Lian-Jie, Asaoka Yoshinari, Tada Motohisa, Sanada Masashi, Nannya Yasuhito, Tanaka Yasuo, Tateishi Keisuke, Ohta Miki, Seto Motoko, Sasahira Naoki, Tada Minoru, Kawabe Takao, Zheng Chang-Qing, Kanai Fumihiko, Ogawa Seishi, Omata Masao

Abstract excerpt

OBJECTIVE: To chart molecular genetic events in pancreatic cancer. METHODS: We analyzed genome-wide copy number alterations and loss of heterozygosity (LOH) in 25 established pancreatic cancer cell lines using a high-density single nucleotide polymorphism (SNP) array. We verified the data using genomic PCR and applied them to clinical samples. RESULTS: Twenty-six homozygous deletion regions were detected in at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18787345
DOI: 10.1159/000155813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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