Article

Whole Genome Copy Number Analyses Reveal a Highly Aberrant Genome in TP53 Mutant Lung Adenocarcinoma Tumors

2021-05-26

Abstract excerpt

<h4>Background: </h4> Genetic alterations are common in non-small cell lung cancer (NSCLC), and DNA mutations and translocations are targets for therapy. Copy number aberrations occur frequently in NSCLC tumors and may influence gene expression and further alter signaling pathways. In this study we aimed to characterize the genomic architecture of NSCLC tumors and to identify genomic differences between tumors str...

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Literature Corpus work: e29e289e-1700-5870-b28d-f1f67483524a
DOI: 10.21203/rs.3.rs-490863/v1

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