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Landscape of somatic allelic imbalances and copy number alterations in human lung carcinoma

1 Oct 2012

Abstract excerpt

Lung cancer is the worldwide leading cause of death from cancer and has been shown to be a heterogeneous disease at the genomic level. To delineate the genomic landscape of copy number alterations, amplifications, loss-of-heterozygosity (LOH), tumor ploidy and copy-neutral allelic imbalance in lung cancer, microarray-based genomic profiles from 2,141 tumors and cell lines including adenocarcinomas (AC, n =...

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PMID: 23023297
DOI: 10.1002/ijc.27879

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